Arginine-Rich Cationic Polypeptides Amplify Lipopolysaccharide-Induced Monocyte Activation

Monocyte Activation Amplify Lipopolysaccharide-Induced Arginine-Rich Cationic Polypeptides

Neutrophil extracellular traps downregulate lipopolysaccharide-induced activation of monocyte-derived dendritic cells.

Polymorphonuclear neutrophils (PMN) play a central role in inflammation and participate in its control, notably by modulating dendritic cell (DC) functions via soluble mediators or cell-cell contacts. Neutrophil extracellular traps (NETs) released by PMN could play a role in this context. To evaluate NET effects on DC maturation, we developed a model based on monocyte-derived DC (moDC) and cali...

L-arginine attenuates lipopolysaccharide-induced lung chemokine production.

Chemokines stimulate the influx of leukocytes into tissues. Their production is regulated by nuclear factor-kappaB (NF-kappaB), an inducible transcription factor under the control of inhibitory factor kappaB-alpha (IkappaB-alpha). We have previously demonstrated that L-arginine (L-Arg) attenuates neutrophil accumulation and pulmonary vascular injury after administration of lipopolysaccharide (L...

Human Monocyte-Derived Dendritic Cells but Not Peptidoglycan-Induced Activation of Lipopolysaccharide- or Poly(I:C)-Induced Erythromycin Differentially Inhibits

effect of bacterial lipopolysaccharide contamination on gutta percha- versus resilon-induced human monocyte cell line toxicity.

cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro.human monocytes from thp-1 cell line were cultured. three millimeters from the tip of each resilon and gutta percha points were cut and directly placed at the bottom of the culture wells. cultured cells were exposed to gutta percha (groups g1 and g2) and resilon (r1 and r2). te...